Artificial cell factory design for shikimate production in Escherichia coli.
Lee HN, Seo SY, Kim HJ, Park JH, Park E, Choi SS, Lee SJ, Kim ES.
Lee HN, et al.
J Ind Microbiol Biotechnol. 2021 Dec 23;48(9-10):kuab043. doi: 10.1093/jimb/kuab043.
J Ind Microbiol Biotechnol. 2021.
PMID: 34227672
Free PMC article.
The genes with negative effects on shikimate biosynthesis, including tyrR, ptsG, and pykA, were disrupted. In contrast, several shikimate biosynthetic pathway genes, including aroB, aroD, aroF, aroG, and aroE, were overexpressed to maximize the glucose uptake and in …
The genes with negative effects on shikimate biosynthesis, including tyrR, ptsG, and pykA, were disrupted. In contrast, several shiki …